Serial changes in liquid biopsy-derived variant allele frequency predict immune checkpoint inhibitor responsiveness in the pan-cancer setting

Serial changes in liquid biopsy-derived variant allele frequency predict immune checkpoint inhibitor responsiveness in the pan-cancer setting

Major immunotherapy challenges include a limited number of predictive biomarkers and the unusual imaging features post-therapy, such as pseudo-progression, which denote immune infiltrate-mediated tumor enlargement. Such phenomena confound clinical decision-making, since the cancer may eventually reg...

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Bibliographic Details
Main Authors: Shumei Kato, Bing Li, Jacob J. Adashek, Seong Won Cha, Daniella Bianchi-Frias, Dajun Qian, Lisa Kim, Tiffany W so, Marcus Mitchell, Naoki Kamei, Robert Hoiness, Jayne Hoo, Phillip N. Gray, Teruaki Iyama, Masahide Kashiwagi, Hsiao-Mei Lu, Razelle Kurzrock
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:OncoImmunology
Subjects:
Immune checkpoint inhibitor
liquid biopsy
response
cancer
Online Access:https://www.tandfonline.com/doi/10.1080/2162402X.2022.2052410

Internet

https://www.tandfonline.com/doi/10.1080/2162402X.2022.2052410

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