Dendritic branch structure compartmentalizes voltage-dependent calcium influx in cortical layer 2/3 pyramidal cells

Dendritic branch structure compartmentalizes voltage-dependent calcium influx in cortical layer 2/3 pyramidal cells

Back-propagating action potentials (bAPs) regulate synaptic plasticity by evoking voltage-dependent calcium influx throughout dendrites. Attenuation of bAP amplitude in distal dendritic compartments alters plasticity in a location-specific manner by reducing bAP-dependent calcium influx. However, it...

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Bibliographic Details
Main Authors: Andrew T Landau, Pojeong Park, J David Wong-Campos, He Tian, Adam E Cohen, Bernardo L Sabatini
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-03-01
Series:eLife
Subjects:
dendrites
calcium
impedance
biophysics
action potentials
Online Access:https://elifesciences.org/articles/76993

Internet

https://elifesciences.org/articles/76993

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