Studies of Tumor Suppressor Genes via Chromosome Engineering

The development and progression of malignant tumors likely result from consecutive accumulation of genetic alterations, including dysfunctional tumor suppressor genes. However, the signaling mechanisms that underlie the development of tumors have not yet been completely elucidated. Discovery of nove...

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Bibliographic Details
Main Authors: Hiroyuki Kugoh, Takahito Ohira, Mitsuo Oshimura
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/8/1/4