Studies of Tumor Suppressor Genes via Chromosome Engineering
The development and progression of malignant tumors likely result from consecutive accumulation of genetic alterations, including dysfunctional tumor suppressor genes. However, the signaling mechanisms that underlie the development of tumors have not yet been completely elucidated. Discovery of nove...
Main Authors: | Hiroyuki Kugoh, Takahito Ohira, Mitsuo Oshimura |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2015-12-01
|
Series: | Cancers |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6694/8/1/4 |
Similar Items
-
Insights into the evolution of mammalian telomerase: Platypus <it>TERT</it> shares similarities with genes of birds and other reptiles and localizes on sex chromosomes
by: Hrdličková Radmila, et al.
Published: (2012-06-01) -
Mapping of the Gene for the Human Telomerase Reverse Transcriptase, hTERT, to Chromosome 5p15.33 by Fluorescence in Situ Hybridization
by: Lisa A. Bryce, et al.
Published: (2000-05-01) -
AST-487 Inhibits RET Kinase Driven TERT Expression in Bladder Cancer
by: Neeraj Agarwal, et al.
Published: (2022-09-01) -
Characterization of the T cell receptor repertoire and melanoma tumor microenvironment upon combined treatment with ipilimumab and hTERT vaccination
by: Espen Basmo Ellingsen, et al.
Published: (2022-09-01) -
Telomerase as a Target for Therapeutic Cancer Vaccines and Considerations for Optimizing Their Clinical Potential
by: Espen Basmo Ellingsen, et al.
Published: (2021-07-01)