Hypoxia-preconditioned WJ-MSC spheroid-derived exosomes delivering miR-210 for renal cell restoration in hypoxia-reoxygenation injury

Hypoxia-preconditioned WJ-MSC spheroid-derived exosomes delivering miR-210 for renal cell restoration in hypoxia-reoxygenation injury

Abstract Background Recent advancements in mesenchymal stem cell (MSC) technology have paved the way for innovative treatment options for various diseases. These stem cells play a crucial role in tissue regeneration and repair, releasing local anti-inflammatory and healing signals. However, challeng...

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Main Authors: Reyhaneh Toghiani, Vajihe Azimian Zavareh, Hanyieh Najafi, Mina Mirian, Negar Azarpira, Samira Sadat Abolmaali, Jaleh Varshosaz, Ali Mohammad Tamaddon
Format: Article
Jezik:English
Izdano: BMC 2024-07-01
Serija:Stem Cell Research & Therapy
Teme:
Wharton jelly-derived mesenchymal stem cells
Hypoxia preconditioning
Exosome
3D culture
Renal ischemia-reperfusion injury
Online dostop:https://doi.org/10.1186/s13287-024-03845-7

Internet

https://doi.org/10.1186/s13287-024-03845-7

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