In Vitro Model of Suppression of the Alloantigen Response by Tolerogenic Dendritic Cells Transfected with Personalized DNA Constructs Encoding HLA Epitopes

In Vitro Model of Suppression of the Alloantigen Response by Tolerogenic Dendritic Cells Transfected with Personalized DNA Constructs Encoding HLA Epitopes

Background: A search for efficient graft rejection modulation techniques for the promotion of durable engraftment remains to be a matter of close study all over the world. Despite the variety of immunosuppressive drugs, the schemes currently used show a lack of selectivity and have a number of side...

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Bibliographic Details
Main Authors: Julia A. Shevchenko, Julia A. Lopatnikova, Julia N. Khantakova, Alexander N. Silkov, Maria S. Kuznetsova, Vasiliy V. Kurilin, Amir Z. Maksyutov, Sergey V. Sennikov
Format: Article
Language:English
Published: IMR Press 2022-05-01
Series:Frontiers in Bioscience-Landmark
Subjects:
mediated immune suppression
mixed lymphocyte culture
t regulatory cells
tolerogenic dendritic cells
dna constructs
hla
mhc
alloantigens
Online Access:https://www.imrpress.com/journal/FBL/27/6/10.31083/j.fbl2706170

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https://www.imrpress.com/journal/FBL/27/6/10.31083/j.fbl2706170

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