Autophagic degradation of CNS myelin maintains axon integrity

Autophagic degradation of CNS myelin maintains axon integrity

(Macro)autophagy is a major lysosome-dependent degradation mechanism which engulfs, removes and recycles unwanted cytoplasmic material, including damaged organelles and toxic protein aggregates. Although a few studies implicate autophagy in CNS demyelinating pathologies, its role, particularly in ma...

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Bibliographic Details
Main Authors: Niki Ktena, Stefanos Ioannis Kaplanis, Irina Kolotuev, Alexandros Georgilis, Emmanouela Kallergi, Vasiliki Stavroulaki, Vassiliki Nikoletopoulou, Maria Savvaki, Domna Karagogeos
Format: Article
Language:English
Published: Shared Science Publishers OG 2022-11-01
Series:Cell Stress
Subjects:
autophagy
myelin
cns
oligodendrocyte
plp
mbp
Online Access:http://www.cell-stress.com/researcharticles/2022a-ktena-cell-stress/

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http://www.cell-stress.com/researcharticles/2022a-ktena-cell-stress/

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