Nuclear Factor Erythroid-2-Related Factor 2 Signaling in the Neuropathophysiology of Inherited Metabolic Disorders

Nuclear Factor Erythroid-2-Related Factor 2 Signaling in the Neuropathophysiology of Inherited Metabolic Disorders

Inherited metabolic disorders (IMDs) are rare genetic conditions that affect multiple organs, predominantly the central nervous system. Since treatment for a large number of IMDs is limited, there is an urgent need to find novel therapeutical targets. Nuclear factor erythroid-2-related factor 2 (Nrf...

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Bibliographic Details
Main Authors: Bianca Seminotti, Mateus Grings, Paolo Tucci, Guilhian Leipnitz, Luciano Saso
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Nrf2 signaling
antioxidant defenses
inherited metabolic disorders
neurometabolism
neurodegeneration
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.785057/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2021.785057/full

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