Delineation of stage specific expression of Plasmodium falciparum EBA-175 by biologically functional region II monoclonal antibodies.

Delineation of stage specific expression of Plasmodium falciparum EBA-175 by biologically functional region II monoclonal antibodies.

The malaria parasite Plasmodium falciparum EBA-175 binds its receptor sialic acids on glycophorin A when invading erythrocytes. The receptor-binding region (RII) contains two cysteine-rich domains with similar cysteine motifs (F1 and F2). Functional relationships between F1 and F2 domains and charac...

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Bibliographic Details
Main Authors: B Kim Lee Sim, David L Narum, Rana Chattopadhyay, Adriana Ahumada, J David Haynes, Steven R Fuhrmann, Jennifer N Wingard, Hong Liang, J Kathleen Moch, Stephen L Hoffman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3077373?pdf=render

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http://europepmc.org/articles/PMC3077373?pdf=render

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