In vivo clearance of nanoparticles by transcytosis across alveolar epithelial cells.

In vivo clearance of nanoparticles by transcytosis across alveolar epithelial cells.

Nanoparticles in polluted air or aerosolized drug nanoparticles predominantly settle in the alveolar lung. Here, we describe a novel, highly effective pathway for the particles to cross the alveolar epithelium and reach the lymph and bloodstream. Amorphous silica nanoparticles, suspended in perfluor...

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Bibliographic Details
Main Authors: Pascal Detampel, Anutosh Ganguly, Sara Tehranian, Francis Green, Santiswarup Singha, Pere Santamaria, Ayodeji A Jeje, Clifford S Cho, Björn Petri, Matthias W Amrein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0223339

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https://doi.org/10.1371/journal.pone.0223339

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