Visfatin Mediates SCLC Cells Migration across Brain Endothelial Cells through Upregulation of CCL2

Visfatin Mediates SCLC Cells Migration across Brain Endothelial Cells through Upregulation of CCL2

Small-cell lung cancer (SCLC) is characterized as an aggressive tumor with brain metastasis. Although preventing SCLC metastasis to the brain is immensely important for survival, the molecular mechanisms of SCLC cells penetrating the blood–brain barrier (BBB) are largely unknown. Recently, visfatin...

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Bibliographic Details
Main Authors: Tingting Liu, Ziwei Miao, Jiusheng Jiang, Shuai Yuan, Wengang Fang, Bo Li, Yuhua Chen
Format: Article
Language:English
Published: MDPI AG 2015-05-01
Series:International Journal of Molecular Sciences
Subjects:
brain metastasis
SCLC
visfatin
transendothelial migration
blood–brain barrier (BBB)
CC chemokine ligand 2 (CCL2)
Online Access:http://www.mdpi.com/1422-0067/16/5/11439

Internet

http://www.mdpi.com/1422-0067/16/5/11439

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