Common Variants in PLXNA4 and Correlation to CSF-related Phenotypes in Alzheimer's Disease

The Plexin-A 4 (PLXNA4) gene, has recently been identified in genome wide association studies (GWAS), as a novel genetic player associated with Alzheimer's disease (AD). Additionally, PLXNA4 genetic variations were also found to increase AD risk by tau pathology in vitro. However, the potential...

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Bibliographic Details
Main Authors: Qiu Han, Yong-An Sun, Yu Zong, Chun Chen, Hui-Fu Wang, Lan Tan, Alzheimer's Disease Neuroimaging Initiative
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2018.00946/full