Blood–Brain Barrier Remodeling in an Organ‐on‐a‐Chip Device Showing Dkk1 to be a Regulator of Early Metastasis

Blood–Brain Barrier Remodeling in an Organ‐on‐a‐Chip Device Showing Dkk1 to be a Regulator of Early Metastasis

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Brain metastases are the most lethal progression events, in part because the biological processes underpinning brain metastases are poorly understood. There is a paucity of realistic models of metastasis, as current in vivo murine models are slow to manifest metastasis. Metabolic and secretory modul...

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Bibliographic Details
Main Authors: Trisha M. Westerhof, Benjamin A. Yang, Nathan M. Merrill, Joel A. Yates, Megan Altemus, Liam Russell, Anna J. Miller, Liwei Bao, Zhifen Wu, Peter J. Ulintz, Carlos A. Aguilar, Aki Morikawa, Maria G. Castro, Sofia D. Merajver, Christopher R. Oliver
Format: Article
Language:English
Published: Wiley-VCH 2023-04-01
Series:Advanced NanoBiomed Research
Subjects:
blood–brain barrier
cancer
dkk-1
metastasis
microenvironments
microfluidic
Online Access:https://doi.org/10.1002/anbr.202200036

Internet

https://doi.org/10.1002/anbr.202200036

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