A maternal high-fat diet predisposes to infant lung disease via increased neutrophil-mediated IL-6 trans-signaling

A maternal high-fat diet predisposes to infant lung disease via increased neutrophil-mediated IL-6 trans-signaling

Summary: A poor maternal diet during pregnancy predisposes the infant to severe lower respiratory tract infections (sLRIs), which, in turn, increases childhood asthma risk; however, the underlying mechanisms remain poorly understood. Here, we show that the offspring of high-fat diet (HFD)-fed mother...

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Bibliographic Details
Main Authors: Bodie Curren, Tufael Ahmed, Ridwan B. Rashid, Ismail Sebina, Md. Al Amin Sikder, Daniel R. Howard, Mariah Alorro, Md. Ashik Ullah, Alec Bissell, Muhammed Mahfuzur Rahman, Michael A. Pearen, Grant A. Ramm, Antiopi Varelias, Stefan Rose-John, Kelli P.A. MacDonald, Robert Hoelzle, Páraic Ó Cuív, Kirsten M. Spann, Paul G. Dennis, Simon Phipps
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Cell Reports
Subjects:
CP: Immunology
CP: Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724013251

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http://www.sciencedirect.com/science/article/pii/S2211124724013251

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