Pacific-Ciguatoxin-2 and Brevetoxin-1 Induce the Sensitization of Sensory Receptors Mediating Pain and Pruritus in Sensory Neurons

Pacific-Ciguatoxin-2 and Brevetoxin-1 Induce the Sensitization of Sensory Receptors Mediating Pain and Pruritus in Sensory Neurons

Ciguatera fish poisoning (CFP) and neurotoxic shellfish poisoning syndromes are induced by the consumption of seafood contaminated by ciguatoxins and brevetoxins. Both toxins cause sensory symptoms such as paresthesia, cold dysesthesia and painful disorders. An intense pruritus, which may become chr...

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Bibliographic Details
Main Authors: Ophélie Pierre, Maxime Fouchard, Nelig Le Goux, Paul Buscaglia, Raphaël Leschiera, Richard J. Lewis, Olivier Mignen, Joachim W. Fluhr, Laurent Misery, Raphaële Le Garrec
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Marine Drugs
Subjects:
ciguatoxin
ciguatera fish poisoning
brevetoxin
neurotoxic shellfish poisoning
sensory disorders
pruritus
Online Access:https://www.mdpi.com/1660-3397/19/7/387

Internet

https://www.mdpi.com/1660-3397/19/7/387

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