Heat-killed Lactobacillus casei subsp. casei 327 promotes colonic serotonin synthesis in mice

Heat-killed Lactobacillus casei subsp. casei 327 promotes colonic serotonin synthesis in mice

We examined the impact of Lactobacillus casei subsp. casei 327 (Lc327) on colonic production of serotonin (5-hydroxytryptamine, 5-HT), a critical regulator of gastrointestinal (GI) function. Heat-killed form of Lc327 was orally administered to BALB/c mice for 14 consecutive days. Significantly highe...

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Bibliographic Details
Main Authors: Takashi Hara, Toshihiro Mihara, Mitsuhisa Ishibashi, Takehisa Kumagai, Toshio Joh
Format: Article
Language:English
Published: Elsevier 2018-08-01
Series:Journal of Functional Foods
Subjects:
Heat-killed probiotics
Lactobacillus casei subsp. casei 327
Serotonin
Tryptophan hydroxylase 1
Enterochromaffin cells
Colon transit
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464618302664

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http://www.sciencedirect.com/science/article/pii/S1756464618302664

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