Reovirus μ2 Protein Impairs Translation to Reduce U5 snRNP Protein Levels

Reovirus μ2 Protein Impairs Translation to Reduce U5 snRNP Protein Levels

Mammalian orthoreovirus (MRV) is a double-stranded RNA virus from the <i>Reoviridae</i> family that infects a large range of mammals, including humans. Recently, studies have shown that MRV alters cellular alternative splicing (AS) during viral infection. The structural protein μ2 appear...

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Bibliographic Details
Main Authors: Simon Boudreault, Carole-Anne Martineau, Laurence Faucher-Giguère, Sherif Abou-Elela, Guy Lemay, Martin Bisaillon
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
reovirus
alternative splicing
U5 SNRNP
polysome profiling
translation inhibition
Online Access:https://www.mdpi.com/1422-0067/24/1/727

Internet

https://www.mdpi.com/1422-0067/24/1/727

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