An efficient rAAV vector for protein expression in cortical parvalbumin expressing interneurons

Abstract Recombinant adeno—associated viruses (rAAV) are extensively used in both research and clinical applications. Despite significant advances, there is a lack of short promoters able to drive the expression of virus delivered genes in specific classes of neurons. We designed an efficient rAAV v...

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Bibliographic Details
Main Authors: Tatiana Tkatch, Kristina Rysevaite-Kyguoliene, Ignas Sabeckis, Deimante Sabeckiene, Dainius H. Pauza, Gytis Baranauskas
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-21867-0