Pan-cancer detection of driver genes at the single-patient resolution
Abstract Background Identifying the complete repertoire of genes that drive cancer in individual patients is crucial for precision oncology. Most established methods identify driver genes that are recurrently altered across patient cohorts. However, mapping these genes back to patients leaves a size...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-02-01
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Series: | Genome Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13073-021-00830-0 |