Pan-cancer detection of driver genes at the single-patient resolution

Abstract Background Identifying the complete repertoire of genes that drive cancer in individual patients is crucial for precision oncology. Most established methods identify driver genes that are recurrently altered across patient cohorts. However, mapping these genes back to patients leaves a size...

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Bibliographic Details
Main Authors: Joel Nulsen, Hrvoje Misetic, Christopher Yau, Francesca D. Ciccarelli
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Genome Medicine
Subjects:
Online Access:https://doi.org/10.1186/s13073-021-00830-0