Nanostructured Lipid Carriers (NLCs) for Oral Peptide Drug Delivery: About the Impact of Surface Decoration

Nanostructured Lipid Carriers (NLCs) for Oral Peptide Drug Delivery: About the Impact of Surface Decoration

This study was aimed to evaluate the impact of surfactants used for nanostructured lipid carriers (NLCs) to provide enzymatic protection for incorporated peptides. Insulin as a model peptide was ion paired with sodium dodecyl sulfate to improve its lipophilicity. Three NLC formulations containing po...

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Bibliographic Details
Main Authors: Iram Shahzadi, Andrea Fürst, Patrick Knoll, Andreas Bernkop-Schnürch
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Pharmaceutics
Subjects:
insulin
nanostructured lipid carriers
pepsin
pancreatin
proteolysis
Online Access:https://www.mdpi.com/1999-4923/13/8/1312

Internet

https://www.mdpi.com/1999-4923/13/8/1312

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