Designing a novel multi‑epitope vaccine against Ebola virus using reverse vaccinology approach

Abstract Ebola virus (EBOV) is a dangerous zoonotic infectious disease. To date, more than 25 EBOV outbreaks have been documented, the majority of which have occurred in Central Africa. The rVSVG-ZEBOV-GP vaccine (ERVEBO), a live attenuated vaccine, has been approved by the US Food and Drug Administ...

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Bibliographic Details
Main Authors: Morteza Alizadeh, Hossein Amini-Khoei, Shahram Tahmasebian, Mahdi Ghatrehsamani, Keihan Ghatreh Samani, Yadolah Edalatpanah, Susan Rostampur, Majid Salehi, Maryam Ghasemi-Dehnoo, Fatemeh Azadegan-Dehkordi, Samira Sanami, Nader Bagheri
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-11851-z