Quantitative Proteomics Reveals Metabolic Reprogramming in Host Cells Induced by Trophozoites and Intermediate Subunit of Gal/GalNAc Lectins from Entamoeba histolytica

Quantitative Proteomics Reveals Metabolic Reprogramming in Host Cells Induced by Trophozoites and Intermediate Subunit of Gal/GalNAc Lectins from Entamoeba histolytica

ABSTRACT Entamoeba histolytica is an intestinal protozoan parasite with remarkable ability to kill and phagocytose host cells, causing amoebic colitis and extraintestinal abscesses. The intermediate subunit (Igl) of galactose (Gal)- and N-acetyl-d-galactosamine (GalNAc)-specific lectins is considere...

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Bibliographic Details
Main Authors: Yanqing Zhao, Xia Li, Ruixue Zhou, Lei Zhang, Lijun Chen, Hiroshi Tachibana, Meng Feng, Xunjia Cheng
Format: Article
Language:English
Published: American Society for Microbiology 2022-04-01
Series:mSystems
Subjects:
Entamoeba histolytica
Gal/GalNAc lectins
quantitative proteomics
metabolic reprogramming
pyruvate kinase
Online Access:https://journals.asm.org/doi/10.1128/msystems.01353-21

Internet

https://journals.asm.org/doi/10.1128/msystems.01353-21

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