Epigenetic alterations in TRAMP mice: epigenome DNA methylation profiling using MeDIP-seq

Epigenetic alterations in TRAMP mice: epigenome DNA methylation profiling using MeDIP-seq

Abstract Purpose We investigated the genomic DNA methylation profile of prostate cancer in transgenic adenocarcinoma of the mouse prostate (TRAMP) cancer model and to analyze the crosstalk among targeted genes and the related functional pathways. Methods Prostate DNA samples from 24-week-old TRAMP a...

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Bibliographic Details
Main Authors: Wenji Li, Ying Huang, Davit Sargsyan, Tin Oo Khor, Yue Guo, Limin Shu, Anne Yuqing Yang, Chengyue Zhang, Ximena Paredes-Gonzalez, Michael Verzi, Ronald P. Hart, Ah-Ng Kong
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Cell & Bioscience
Subjects:
MeDIP-seq
Epigenetics
DNA methylation
TRAMP
Prostate cancer
Online Access:http://link.springer.com/article/10.1186/s13578-018-0201-y

Internet

http://link.springer.com/article/10.1186/s13578-018-0201-y

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