Early Antibiotic Exposure Alters Intestinal Development and Increases Susceptibility to Necrotizing Enterocolitis: A Mechanistic Study

Early Antibiotic Exposure Alters Intestinal Development and Increases Susceptibility to Necrotizing Enterocolitis: A Mechanistic Study

Increasing evidence suggests that prolonged antibiotic therapy in preterm infants is associated with increased mortality and morbidities, such as necrotizing enterocolitis (NEC), a devastating gastrointestinal pathology characterized by intestinal inflammation and necrosis. While a clinical correlat...

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Bibliographic Details
Main Authors: Hala Chaaban, Maulin M. Patel, Kathryn Burge, Jeffrey V. Eckert, Cristina Lupu, Ravi S. Keshari, Robert Silasi, Girija Regmi, MaJoi Trammell, David Dyer, Steven J. McElroy, Florea Lupu
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Microorganisms
Subjects:
necrotizing enterocolitis
intestinal permeability
intestinal development
antibiotics
preterm infant
microbiome
Online Access:https://www.mdpi.com/2076-2607/10/3/519

Internet

https://www.mdpi.com/2076-2607/10/3/519

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