Impact of valganciclovir therapy on severe IRIS-Kaposi Sarcoma mortality: An open-label, parallel, randomized controlled trial.

<h4>Introduction</h4>High HHV-8 viral load (VL) in Kaposi Sarcoma (KS) has been associated with Severe Immune Reconstitution Inflammatory Syndrome (Severe-IRIS-KS), which can occur after initiating cART, and leads to high mortality, particularly in patients with pulmonary involvement. We...

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Main Authors: Patricia Volkow, Leslie Chavez Galan, Lucero Ramon-Luing, Judith Cruz-Velazquez, Patricia Cornejo-Juarez, Isabel Sada-Ovalle, Rogelio Perez-Padilla, Beda Islas-Muñoz, Kaposi Sarcoma Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0280209