The Role of Intra-Tumoral Heterogeneity and Its Clinical Relevance in Epithelial Ovarian Cancer Recurrence and Metastasis

Epithelial ovarian cancer is the deadliest gynecologic cancer, due in large part to recurrent tumors. Recurrences tend to have metastasized, mainly in the peritoneal cavity and developed resistance to the first line chemotherapy. Key to the progression and ultimate lethality of ovarian cancer is the...

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Bibliographic Details
Main Authors: Cai M. Roberts, Carlos Cardenas, Roslyn Tedja
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/11/8/1083