Characterizing immune variation and diagnostic indicators of preeclampsia by single-cell RNA sequencing and machine learning

Characterizing immune variation and diagnostic indicators of preeclampsia by single-cell RNA sequencing and machine learning

Abstract Preeclampsia is a multifactorial and heterogeneous complication of pregnancy. Here, we utilize single-cell RNA sequencing to dissect the involvement of circulating immune cells in preeclampsia. Our findings reveal downregulation of immune response in lymphocyte subsets in preeclampsia, such...

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Bibliographic Details
Main Authors: Wenwen Zhou, Yixuan Chen, Yuhui Zheng, Yong Bai, Jianhua Yin, Xiao-Xia Wu, Mei Hong, Langchao Liang, Jing Zhang, Ya Gao, Ning Sun, Jiankang Li, Yiwei Zhang, Linlin Wu, Xin Jin, Jianmin Niu
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05669-2

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https://doi.org/10.1038/s42003-023-05669-2

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