Oral administration of heat-killed Mycobacterium manresensis delays progression towards active tuberculosis in C3HeB/FeJ mice

Oral administration of heat-killed Mycobacterium manresensis delays progression towards active tuberculosis in C3HeB/FeJ mice

Low-dose tolerance using heat-killed mycobacteria has been tested as a means of stopping progression towards active tuberculosis (TB) lesions in a human-like murine model using C3HeB/FeJ mice. In the present study, we studied the effect of different treatment schedules with heat-killed non-tuberculo...

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Bibliographic Details
Main Authors: Paula eCardona, Elena eMarzo-Escartín, Gustavo eTapia, Jorge eDíaz, Vanessa eGarcía, Ismael eVarela, Cristina eVilaplana, Pere-Joan eCardona
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Microbiology
Subjects:
Mice
Neutrophils
Tuberculosis
tolerance
Tregs
C3HeB/FeJ
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01482/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01482/full

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