An Update on the Molecular Basis of Phosphoantigen Recognition by Vγ9Vδ2 T Cells
About 1–5% of human blood T cells are Vγ9Vδ2 T cells. Their hallmark is the expression of T cell antigen receptors (TCR) whose γ-chains contain a rearrangement of Vγ9 with JP (<i>TRGV9JP</i> or Vγ2Jγ1.2) and are paired with Vδ2 (<i>TRDV2</i>)-containing δ-chains. These TCRs r...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-06-01
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| Series: | Cells |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4409/9/6/1433 |