Cyclin B2 impairs the p53 signaling in nasopharyngeal carcinoma

Cyclin B2 impairs the p53 signaling in nasopharyngeal carcinoma

Abstract Background Cyclin B2 (CCNB2), a member of the cyclin family, is an oncogene in multiple cancers, including nasopharyngeal carcinoma (NPC). However, the epigenetics mechanism for CCNB2 overexpression in NPC remains unclear. This study dissects the regulatory role of CCNB2 in NPC and the mole...

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Bibliographic Details
Main Authors: Qinsong Liu, Yong Yuan, Xiaofen Shang, Lu Xin
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Cancer
Subjects:
JMJD6
CCNB2
p53 pathway
Methylation
Nasopharyngeal carcinoma
Online Access:https://doi.org/10.1186/s12885-023-11768-4

Internet

https://doi.org/10.1186/s12885-023-11768-4

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