Alanyl-glutamine attenuates 5-fluorouracil-induced intestinal mucositis in apolipoprotein E-deficient mice

Alanyl-glutamine attenuates 5-fluorouracil-induced intestinal mucositis in apolipoprotein E-deficient mice

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Apolipoprotein E (APOE=gene, apoE=protein) is a known factor regulating the inflammatory response that may have regenerative effects during tissue recovery from injury. We investigated whether apoE deficiency reduces the healing effect of alanyl-glutamine (Ala-Gln) treatment, a recognized gut-trophi...

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Bibliographic Details
Main Authors: C.V. Araújo, C.R. Lazzarotto, C.C. Aquino, I.L. Figueiredo, T.B. Costa, L.A. de Oliveira Alves, R.A. Ribeiro, L.R. Bertolini, A.A.M. Lima, G.A.C. Brito, R.B. Oriá
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2015-04-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Apolipoprotein E
5-Fluorouracil
Alanyl-glutamine
mucositis
mice
Online Access:http://www.scielo.br/pdf/bjmbr/v48n6/1414-431X-bjmbr-1414-431X20144360.pdf

Internet

http://www.scielo.br/pdf/bjmbr/v48n6/1414-431X-bjmbr-1414-431X20144360.pdf

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