Natural and engineered cyclodipeptides: Biosynthesis, chemical diversity, and engineering strategies for diversification and high-yield bioproduction.

Cyclodipeptides are diverse chemical scaffolds that show a broad range of bioactivities relevant for medicine, agriculture, chemical catalysis, and material sciences. Cyclodipeptides can be synthesized enzymatically through two unrelated enzyme families, non-ribosomal peptide synthetases (NRPS) and...

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Bibliographic Details
Main Authors: Wahyu Setia Widodo, Sonja Billerbeck
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Engineering Microbiology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667370322000571