Apoptin Overexpression Efficiently Amplified Cytotoxic Effects of PI3K Inhibition Using BKM120 in Lymphoblastic Leukemia Cell Lines

Purpose: Although the complex structure of acute lymphoblastic leukemia (ALL) andinvolvement of diverse pathways in its pathogenesis have put an obstacle in the way of efficienttreatments, identification of strategies to manipulate the genome of neoplastic cells has madethe treatment prospective mor...

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Bibliographic Details
Main Authors: Ali Anjam-Najmedini, Rohollah Vahabpour, Ava Safaroghli-Azar, Alireza Kazemi, Parvaneh Movahhed, Majid Momeny, Davood Bashash
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2022-05-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Online Access:https://apb.tbzmed.ac.ir/PDF/apb-12-613.pdf