Chaperonin GroEL/GroES over-expression promotes multi-drug resistance in E. coli following exposure to aminoglycoside antibiotics
Antibiotic resistance is an increasing challenge to modern healthcare. Aminoglycoside antiobiotics cause translation corruption and protein misfolding and aggregation in Escherichia coli. We previously showed that chaperonin GroEL/GroES depletion and overexpression sensitize and promote short-term t...
| Glavni autori: | , , |
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| Format: | Članak |
| Jezik: | English |
| Izdano: |
Frontiers Media S.A.
2016-01-01
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| Serija: | Frontiers in Microbiology |
| Teme: | |
| Online pristup: | http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01572/full |