Phrenic nerve stimulation mitigates hippocampal and brainstem inflammation in an ARDS model

Phrenic nerve stimulation mitigates hippocampal and brainstem inflammation in an ARDS model

Rationale: In porcine healthy-lung and moderate acute respiratory distress syndrome (ARDS) models, groups that received phrenic nerve stimulation (PNS) with mechanical ventilation (MV) showed lower hippocampal apoptosis, and microglia and astrocyte percentages than MV alone.Objectives: Explore wheth...

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Bibliographic Details
Main Authors: Thiago G. Bassi, Elizabeth C. Rohrs, Karl C. Fernandez, Marlena Ornowska, Michelle Nicholas, Jessica Wittmann, Matt Gani, Doug Evans, Steven C. Reynolds
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Physiology
Subjects:
mechanical ventilalion
brainstem inflammation
ARDS
neuroinflammation
phrenic nerve stimulation
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1182505/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2023.1182505/full

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