Exploring biomarkers for prognosis and neoadjuvant chemosensitivity in rectal cancer: Multi-omics and ctDNA sequencing collaboration

Exploring biomarkers for prognosis and neoadjuvant chemosensitivity in rectal cancer: Multi-omics and ctDNA sequencing collaboration

IntroductionThis study aimed to identified the key genes and sequencing metrics for predicting prognosis and efficacy of neoadjuvant chemotherapy (nCT) in rectal cancer (RC) based on genomic DNA sequencing in samples with different origin and multi-omics association database.MethodsWe collected 16 R...

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Bibliographic Details
Main Authors: Xiu-Feng Jiang, Bo-Miao Zhang, Fen-Qi Du, Jun-Nan Guo, Dan Wang, Yi-En Li, Shen-Hui Deng, Bin-Bin Cui, Yan-Long Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
rectal cancer
cell-free DNA
genomic sequencing
multi-omics
prognosis
neoadjuvant chemotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1013828/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1013828/full

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