The role of bone marrow microenvironment (BMM) cells in acute myeloid leukemia (AML) progression: immune checkpoints, metabolic checkpoints, and signaling pathways

The role of bone marrow microenvironment (BMM) cells in acute myeloid leukemia (AML) progression: immune checkpoints, metabolic checkpoints, and signaling pathways

Abstract Acute myeloid leukemia (AML) comprises a multifarious and heterogeneous array of illnesses characterized by the anomalous proliferation of myeloid cells in the bone marrow microenvironment (BMM). The BMM plays a pivotal role in promoting AML progression, angiogenesis, and metastasis. The im...

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Bibliographic Details
Main Authors: Maryam Bakhtiyari, Mahsa Liaghat, Fatemeh Aziziyan, Hooriyeh Shapourian, Sheida Yahyazadeh, Maedeh Alipour, Shaghayegh Shahveh, Fahimeh Maleki-Sheikhabadi, Hossein Halimi, Razieh Forghaniesfidvajani, Hamidreza Zalpoor, Mohsen Nabi-Afjadi, Majid Pornour
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Cell Communication and Signaling
Subjects:
Acute myeloid leukemia
Bone marrow microenvironment
Cancer metabolism
Metabolic checkpoint
Immune checkpoint
Angiogenesis
Online Access:https://doi.org/10.1186/s12964-023-01282-2

Internet

https://doi.org/10.1186/s12964-023-01282-2

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