The Antinociceptive Responses of MTDZ to Paclitaxel−Induced Peripheral Neuropathy and Acute Nociception in Mice: Behavioral, Pharmacological, and Biochemical Approaches

The Antinociceptive Responses of MTDZ to Paclitaxel−Induced Peripheral Neuropathy and Acute Nociception in Mice: Behavioral, Pharmacological, and Biochemical Approaches

The efficacy of 5-((4-methoxyphenyl)thio)benzo[c][1,2,5] thiodiazole (MTDZ) in mitigating paclitaxel (PTX)-induced peripheral neuropathy was investigated in male and female Swiss mice. The study examined the effects of MTDZ on various pathways, including transient receptor potential cation channel s...

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Bibliographic Details
Main Authors: Ketlyn P. da Motta, Carolina C. Martins, Vanessa M. Macedo, Beatriz F. dos Santos, Nelson Luís De C. Domingues, Cristiane Luchese, Ethel A. Wilhelm
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Pharmaceuticals
Subjects:
paclitaxel
peripheral neuropathy
sulfur compound
nociception
Online Access:https://www.mdpi.com/1424-8247/16/9/1217

Internet

https://www.mdpi.com/1424-8247/16/9/1217

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