Evaluation of the immune-modulatory, anti-oxidant, proliferative, and anti-apoptotic effects of nano-silymarin on mesenchymal stem cells isolated from multiple sclerosis patients' adipose tissue sources

Silymarin (SL) has a long history of use for the treatment of a variety of diseases, but several limitations, such as poor bioavailability and negligible solubility, have restricted its successful translation in a clinical setting. However, the nano-micelle delivery system is a highly reproducible m...

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Main Authors: Fahimeh Lavi Arab, Forouzan Yousefi, Mahmoud Reza Jaafari, Arezoo Rajabian, Hassan Dana, Nafiseh Tabasi, Saeed Behboodifar, Arezoo Faridzadeh, Mahmoud Mahmoudi
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Journal of Functional Foods
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Online Access:http://www.sciencedirect.com/science/article/pii/S1756464623005583