Blood vessel hyperpermeability and pathophysiology in human tumour xenograft models of breast cancer: a comparison of ectopic and orthotopic tumours

<p>Abstract</p> <p>Background</p> <p>Human tumour xenografts in immune compromised mice are widely used as cancer models because they are easy to reproduce and simple to use in a variety of pre-clinical assessments. Developments in nanomedicine have led to the use of tu...

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Bibliographic Details
Main Authors: Ho Karyn S, Poon Peter C, Owen Shawn C, Shoichet Molly S
Format: Article
Language:English
Published: BMC 2012-12-01
Series:BMC Cancer
Subjects:
Online Access:http://www.biomedcentral.com/1471-2407/12/579