Structural and functional analyses of Burkholderia pseudomallei BPSL1038 reveal a Cas-2/VapD nuclease sub-family

Structural and functional analyses of Burkholderia pseudomallei BPSL1038 reveal a Cas-2/VapD nuclease sub-family

Abstract Burkholderia pseudomallei is a highly versatile pathogen with ~25% of its genome annotated to encode hypothetical proteins. One such hypothetical protein, BPSL1038, is conserved across seven bacterial genera and 654 Burkholderia spp. Here, we present a 1.55 Å resolution crystal structure of...

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Bibliographic Details
Main Authors: Sofiyah Shaibullah, Nurshahirah Shuhaimi, De-Sheng Ker, Nurhikmah Mohd-Sharif, Kok Lian Ho, Aik-Hong Teh, Jitka Waterman, Thean-Hock Tang, Rui-Rui Wong, Sheila Nathan, Rahmah Mohamed, Min Jia Ng, Shin-Yee Fung, Mohd Anuar Jonet, Mohd Firdaus-Raih, Chyan Leong Ng
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05265-4

Internet

https://doi.org/10.1038/s42003-023-05265-4

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