Pax-5 Protein Expression Is Regulated by Transcriptional 3′UTR Editing

Pax-5 Protein Expression Is Regulated by Transcriptional 3′UTR Editing

The <i>Pax-5</i> gene encodes a transcription factor that is essential for B-cell commitment and maturation. However, <i>Pax-5</i> deregulation is associated with various cancer lesions, notably hematopoietic cancers. Mechanistically, studies have characterized genetic altera...

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Bibliographic Details
Main Authors: Annie-Pier Beauregard, Brandon Hannay, Ehsan Gharib, Nicolas Crapoulet, Nicholas Finn, Roxann Guerrette, Amélie Ouellet, Gilles A. Robichaud
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cells
Subjects:
<i>Pax-5</i>
alternative polyadenylation
3′UTR editing
B-cell
cancer
alternative splicing
Online Access:https://www.mdpi.com/2073-4409/11/1/76

Internet

https://www.mdpi.com/2073-4409/11/1/76

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