Immunomodulation Eliminates Inflammation in the Hippocampus in Experimental Autoimmune Encephalomyelitis, but Does Not Ameliorate Anxiety-Like Behavior

Immunomodulation Eliminates Inflammation in the Hippocampus in Experimental Autoimmune Encephalomyelitis, but Does Not Ameliorate Anxiety-Like Behavior

Multiple sclerosis (MS) is an autoimmune disease targeting the central nervous system, characterized by an unpredictable disease course and a wide range of symptoms. Emotional and cognitive deficits are now recognized as primary disease manifestations and not simply the consequence of living with a...

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Bibliographic Details
Main Authors: Pece Kocovski, Nuzhat Tabassum-Sheikh, Stephanie Marinis, Phuc T. Dang, Matthew W. Hale, Jacqueline M. Orian
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
EAE (experimental autoimmune encephalomyelitis)
hippocampus
immunomodulation
multiple sclerosis
anxiety and major depression
S1PR
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.639650/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.639650/full

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