Antagonistic action of leaf juice of Brassica rapa on damaged mouse by cyclophospamide(芜菁叶汁对环磷酰胺致小鼠突变的拮抗作用)

用清洁级ICR小鼠作动物整体试验,通过小鼠骨髓嗜多染红细胞(PCE)的微核试验、小鼠骨髓染色体畸变试验等方法.测定芜菁叶汁对环磷酰胺(Cyclophospamide,以下简称CP)引起遗传物质损伤的保护拮抗效应.灌胃(ig)不同剂量叶汁均使小鼠骨髓PCE微核率、骨髓染色体畸变率有所下降,且具有明显的剂量效应.芜菁叶汁对环磷酰胺引起小鼠的损伤具有明显的拮抗作用,提示芜菁叶汁具有一定的抗突变作用....

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Bibliographic Details
Main Authors: QIANXiao-wei(钱晓薇), ZHUMu-yuan(朱睦元), KONGXiao-ying(孔小映), XUCheng-wu(许成武), ZHUXiao-chun(朱小春)
Format: Article
Language:zho
Published: Zhejiang University Press 2003-01-01
Series:Zhejiang Daxue xuebao. Lixue ban
Subjects:
Online Access:https://doi.org/zjup/1008-9497.2003.30.1.89-92