Costunolide alleviated DDC induced ductular reaction and inflammatory response in murine model of cholestatic liver disease

Costunolide alleviated DDC induced ductular reaction and inflammatory response in murine model of cholestatic liver disease

Purpose: Cholestatic liver diseases are groups of hepatobiliary diseases without curative drug-based therapy options. Regulation of bile acid (BA) metabolism, hepatoperiductal fibrosis, and inflammatory response indicated present novel methods for the treatment of cholestatic liver disease. Costunol...

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Bibliographic Details
Main Authors: Juan Hao, Xiaoyu Shen, Kan Lu, Yi Xu, Yiyue Chen, Jibo Liu, Xiaohong Shao, Chunling Zhu, Yaqin Ding, Xin Xie, Jian Wu, Quanjun Yang
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Journal of Traditional and Complementary Medicine
Subjects:
Costunolide
Cholestatic liver disease
Bile acid metabolism
Inflammatory response
Ductular reaction
Online Access:http://www.sciencedirect.com/science/article/pii/S2225411023000226

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http://www.sciencedirect.com/science/article/pii/S2225411023000226

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