Optimization and validation of sample preparation for metagenomic sequencing of viruses in clinical samples

Optimization and validation of sample preparation for metagenomic sequencing of viruses in clinical samples

Abstract Background Sequence-specific PCR is the most common approach for virus identification in diagnostic laboratories. However, as specific PCR only detects pre-defined targets, novel virus strains or viruses not included in routine test panels will be missed. Recently, advances in high-throughp...

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Bibliographic Details
Main Authors: Dagmara W. Lewandowska, Osvaldo Zagordi, Fabienne-Desirée Geissberger, Verena Kufner, Stefan Schmutz, Jürg Böni, Karin J. Metzner, Alexandra Trkola, Michael Huber
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Microbiome
Subjects:
Metagenomic sequencing
Clinical samples
Virus diagnostics
Sample preparation
Online Access:http://link.springer.com/article/10.1186/s40168-017-0317-z

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http://link.springer.com/article/10.1186/s40168-017-0317-z

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