Reactive astrocytes contribute to decreased blood-brain barrier integrity after impulsive pressure loading in vitro

Although it has been reported that blood brain barrier (BBB) disruption following head impact can lead to increased vascular permeability and subsequent brain injury, the influence of pressure loading on BBB dysfunction is not fully understood. In this study, we exposed in vitro BBB models to impuls...

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Bibliographic Details
Main Authors: Hiromichi NAKADATE, Shigeru AOMURA, Akiyoshi NISHIMURA
Format: Article
Language:English
Published: The Japan Society of Mechanical Engineers 2021-05-01
Series:Journal of Biomechanical Science and Engineering
Subjects:
Online Access:https://www.jstage.jst.go.jp/article/jbse/16/2/16_21-00075/_pdf/-char/en