Metabolic dynamics restricted by conserved carriers: Jamming and feedback.

To uncover the processes and mechanisms of cellular physiology, it first necessary to gain an understanding of the underlying metabolic dynamics. Recent studies using a constraint-based approach succeeded in predicting the steady states of cellular metabolic systems by utilizing conserved quantities...

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Bibliographic Details
Main Authors: Tetsuhiro S Hatakeyama, Chikara Furusawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-11-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1005847