Polycomb response elements reduce leaky expression of Cas9 under temperature-inducible <i>Hsp70Bb</i> promoter in <i>Drosophila melanogaster</i>

AbstractHeat-shock-inducible expression of genes through the use of heat-inducible promoters is commonly used in research despite leaky expression of downstream genes of interest without targeted induction (i.e. heat shock). The development of non-leaky inducible expression systems i...

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Bibliographic Details
Main Authors: Natalie Warsinger-Pepe, Carly Chang, Connor R Desroberts, Omar S Akbari
Format: Article
Language:English
Published: Oxford University Press 2023-01-01
Series:G3: Genes, Genomes, Genetics
Online Access:https://academic.oup.com/g3journal/article-lookup/doi/10.1093/g3journal/jkad024