Mifepristone Followed by Misoprostol Compared with Placebo Followed by Misoprostol as Medical Treatment for Early Pregnancy Loss (the Triple M trial): A Double-Blind Placebo-Controlled Randomised Trial

Background: Worldwide, millions of women seek treatment for early pregnancy loss (EPL) annually. Medical management with misoprostol is widely used, but only effective 60% of the time. Pre-treatment with mifepristone prior to misoprostol might improve the success rate of medical management. Methods:...

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Main Authors: Charlotte HAMEL, Sjors COPPUS, Joyce VAN DEN BERG, Esther HINK, Jacoba VAN SEETERS, Paul VAN KESTEREN, Ashley MERIEN, Bas TORRENGA, Rafli VAN DE LAAR, Josien Terwisscha VAN SCHELTINGA, Ingrid GAUGLER-SENDEN, Peppino GRAZIOSI, Minouche VAN RUMSTE, Ewka NELISSEN, Frank VANDENBUSSCHE, Marcus SNIJDERS
Format: Article
Language:English
Published: World Scientific Publishing 2022-09-01
Series:Fertility & Reproduction
Online Access:https://www.worldscientific.com/doi/10.1142/S2661318222740115